Protease Inhibitors as Ad-hoc Antibiotics
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چکیده
Received: December 08, 2015 Revised: April 26, 2016 Accepted: April 27, 2016 Abstract: Background: Proteases are important enzymes that can degrade proteins and are found in animals, plants, bacteria, fungi and viruses. The action of proteases can be controlled by Protease Inhibitors (PIs), chemical or proteinaceous in nature that can block the active site of protease. Since the step catalyzed by proteases may play important role in life cycle of microbes, hindering the action of proteases by PIs may act as therapeutic intervention for microbial infection.
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تاریخ انتشار 2016